MSAT Technician

Summary of the role

A Manufacturing Science and Technology (MSAT) Technician provides hands-on, technical support to the MSAT team. While a Scientist focuses on the research, development, and high-level problem-solving, a Technician is responsible for the practical execution of those plans. They are the “doers” who ensure the processes run smoothly and accurately on the ground.

Typical Duties

Whether in advanced therapies or wider life sciences, the core duties are very similar, but the specific tasks and equipment will differ:

• Manufacturing Support: You’ll be directly involved in manufacturing activities, preparing equipment, media, and materials according to Standard Operating Procedures (SOPs). You’ll ensure the correct execution of the manufacturing process, meticulously following every step of the batch record.
• Process Monitoring: You will collect and record data, perform in-process checks, and monitor equipment to ensure everything is operating within the specified parameters.
• Troubleshooting: If a minor issue arises during a run, you’ll be the first to identify it and, depending on your experience, you may be responsible for helping to resolve it or escalating it to a senior technician or scientist.
• Equipment Maintenance: Technicians are often responsible for the day-to-day cleaning, maintenance, and calibration of equipment, as well as the upkeep of the cleanroom or lab environment.
• Documentation: Accurate and timely completion of batch records and other GMP documentation is a crucial part of this role, as it’s a key part of maintaining regulatory compliance.

The specific context dictates the day-to-day work:

Advanced Therapies (Cell and Gene): Your work would be primarily in a sterile, cleanroom environment. Tasks would involve handling cell cultures, operating specialised equipment like bioreactors for cell expansion, and working with complex, single-use systems to ensure no contamination. Aseptic technique is a fundamental skill.

Wider Life Sciences (e.g. Biologics, Vaccines): You might work with larger-scale equipment like stainless steel bioreactors. Your focus would be on processes like fermentation, chromatography for protein purification, and filtration. The scale of the work is generally much larger, and you’ll be dealing with different types of raw materials and products.

Key Skills and Qualifications (UK)

Essential Qualifications: A degree is not always a requirement. Many technicians start with a Level 3 or 4 apprenticeship, a BTEC, or a HND in a relevant science or engineering subject. A good foundation in biology, chemistry, or biotechnology is key.

Essential Skills:

• Attention to Detail: This is arguably the most important skill. Following SOPs and completing documentation without error is non-negotiable in a regulated environment.
• Practical Aptitude: You need to be comfortable with hands-on work and have a good understanding of how equipment operates.
• Problem-Solving: The ability to identify issues and think logically to find a solution is critical.
• Communication: Clear communication is essential, both for updating colleagues and for accurately documenting your work.
• Teamwork: You’ll be working as part of a close-knit team, often in shifts.

Desirable Qualifications: Experience in a GMP-regulated environment and knowledge of aseptic techniques (for advanced therapies) or bioprocessing (for wider life sciences) would make you a very strong candidate.

Salary Expectations (UK)

Starting Salary: For an MSAT Technician, the starting salary is typically in the range of £25,000 – £32,000 per year. This can vary based on location and the company.

After 3-4 Years: With a few years of experience and a demonstrated ability to take on more responsibility, a technician can expect to earn between £35,000 – £45,000. Experienced technicians can often progress into senior technician roles or even transition to a Scientist role with further education or training.